MRT68921 is primarily used in research settings to study autophagy, a cellular process involved in the degradation and recycling of damaged or unnecessary cellular components. It acts as a potent inhibitor of ULK1, a key kinase that regulates the initiation of autophagy. By inhibiting ULK1, MRT68921 helps researchers understand the role of autophagy in various biological processes, including cancer, neurodegenerative diseases, and immune responses. Its application is crucial in exploring potential therapeutic strategies targeting autophagy-related pathways. Additionally, MRT68921 is utilized in preclinical studies to investigate its effects on cell survival, metabolism, and stress responses, providing insights into its potential as a drug candidate for diseases where autophagy modulation is beneficial.