4-Methoxy-2-(trimethylsilyl)phenyl Trifluoromethanesulfonate
≥95%(GC)
Reagent
Code: #84217
CAS Number
556812-41-0
blur_circular Chemical Specifications
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Molecular Information
Weight
328.38 g/mol
Formula
C₁₁H₁₅F₃O₄SSi
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Storage & Handling
Density
1.25
Storage
Room temperature, dry, inert gas storage
description Product Description
This compound is a substituted aryl triflate, primarily used as an electrophilic reagent in organic synthesis, particularly in cross-coupling reactions such as Suzuki, Heck, and Stille couplings. The trifluoromethanesulfonate (triflate) group acts as a highly reactive leaving group, facilitating the formation of carbon-carbon and carbon-heteroatom bonds for the synthesis of complex organic compounds. It is especially valuable as a building block in the preparation of pharmaceuticals, agrochemicals, and advanced materials. The 4-methoxy substituent provides electronic effects that influence reactivity, while the ortho-trimethylsilyl group enhances stability, directs regioselectivity, and enables further functionalizations, making it a preferred intermediate in demanding synthetic procedures.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Colorless to Light orange to Yellow clear liquid |
| Purity (%) | 95-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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