o-Tolyl trifluoromethanesulfonate is an aryl triflate widely used as a reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura, Heck, and Stille couplings for the formation of carbon-carbon and carbon-heteroatom bonds. It functions as an electrophilic coupling partner, with the trifluoromethanesulfonate group acting as an excellent leaving group superior to halides in many cases. This compound is essential in the synthesis of pharmaceuticals, agrochemicals, and complex organic molecules, including natural products and materials, owing to its stability, high reactivity under mild conditions, and compatibility with sensitive functional groups.