1-Iodo-2,3,4-Trifluorobenzene is primarily used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Its unique structure, combining iodine and fluorine substituents, makes it valuable for constructing complex molecules through cross-coupling reactions, such as Suzuki or Sonogashira couplings. It is also employed in the development of liquid crystals and electronic materials due to its electronic properties and stability. Additionally, it serves as a building block in the synthesis of fluorinated aromatic compounds, which are often used in advanced materials and specialty chemicals.