2-(3-Bromo-4-fluorophenyl)-1,3-dioxolane
≥95%
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Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. The 1,3-dioxolane moiety acts as a protecting group for the corresponding aldehyde, enabling selective modification of the aryl ring while preventing unwanted side reactions. This structure makes it valuable in medicinal chemistry for creating analogs with improved biological activity. Also employed in research settings to develop fluorinated organic molecules, where the fluorine atom enhances metabolic stability and binding affinity. Commonly utilized in cross-coupling reactions such as Suzuki-Miyaura to build complex aromatic systems in drug discovery.
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