Widely used in organic synthesis, especially in cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. Its dual halogen functionality allows selective sequential reactions—bromine typically reacts first due to its higher reactivity in many catalytic systems, enabling stepwise construction of complex aromatic molecules. Commonly employed in pharmaceutical and agrochemical research for building substituted aromatic intermediates. Also used in the synthesis of functional materials, including organic semiconductors and liquid crystals, where precise substitution patterns are required.