Widely used in organic synthesis, especially in cross-coupling reactions such as Suzuki, Stille, and Ullmann reactions, due to the presence of multiple halogen atoms with different reactivities. The iodine atom is highly reactive and typically participates first in coupling processes, allowing selective sequential functionalization. This makes the compound valuable in the preparation of complex aromatic structures, pharmaceuticals, agrochemicals, and advanced materials like organic semiconductors. Its versatility in stepwise transformations supports its use in research and development of new chemical entities.