1,3-Bis(bromomethyl)-5-iodobenzene
95%
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Used as a key intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and functional materials. Its multiple reactive sites—two bromomethyl groups and an iodo substituent—allow selective stepwise coupling reactions, making it valuable in constructing complex molecules. Commonly employed in cross-coupling reactions such as Suzuki or Heck reactions, where the iodo group participates in palladium-catalyzed bond formation. The bromomethyl groups can be displaced to introduce heterocycles, polymers, or bioactive moieties. Also applied in the development of covalent inhibitors and as a building block in supramolecular chemistry and dendrimer synthesis. Its versatility supports use in medicinal chemistry for creating targeted drug candidates and in materials science for designing conjugated systems.
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