1-Bromo-4-(3,3,3-trifluoroprop-1-yn-1-yl)benzene
97%
Reagent
Code: #131481
CAS Number
7119-09-7
blur_circular Chemical Specifications
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Molecular Information
Weight
249.03 g/mol
Formula
C₉H₄BrF₃
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Registry Numbers
MDL Number
MFCD30470981
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Physical Properties
Melting Point
21-22 °C
Boiling Point
121-122 °C at 80 mmHg
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions involving palladium-catalyzed cross-coupling such as Sonogashira and Suzuki couplings. Its bromo and trifluoropropynyl functional groups allow for selective modifications, making it valuable in building complex fluorinated organic molecules. The presence of the trifluoropropynyl group enhances metabolic stability and lipophilicity in bioactive compounds, which is advantageous in drug design. It is also employed in materials science for developing fluorinated conjugated systems used in organic electronics.
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