1-Bromo-3,6-dimethoxy-2-fluorobenzene
95%
Reagent
Code: #129863
CAS Number
1783710-38-2
blur_circular Chemical Specifications
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Molecular Information
Weight
235.05 g/mol
Formula
C₈H₈BrFO₂
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Registry Numbers
MDL Number
MFCD28738437
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Physical Properties
Boiling Point
242.7±35.0 °C(Predicted)
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Storage & Handling
Density
1.489±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions where selective functionalization is required. Its structure allows for directed ortho-metalation, making it valuable in the preparation of complex organic molecules. Commonly employed in cross-coupling reactions such as Suzuki or Heck reactions to build biaryl systems. Also utilized in the development of fluorinated compounds for medicinal chemistry due to the presence of the fluorine atom, which can enhance metabolic stability and binding affinity.
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