2-Phenylpyrimidine-5-boronic acid is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is essential for forming carbon-carbon bonds, enabling the creation of complex organic molecules, including pharmaceuticals and agrochemicals. Its boronic acid group acts as a key functional group, facilitating the coupling with aryl or vinyl halides in the presence of a palladium catalyst. Additionally, it serves as a building block in the development of bioactive compounds, such as kinase inhibitors, which are crucial in cancer research and treatment. Its stability and reactivity make it a valuable reagent in medicinal chemistry and material science.