Benzofuran-5-ylboronic acid is widely used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is essential for forming carbon-carbon bonds, making it valuable in the production of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group acts as a key intermediate, enabling the attachment of benzofuran moieties to various aromatic or heteroaromatic compounds. This chemical is also employed in the development of bioactive molecules, including potential drug candidates, due to the benzofuran structure's presence in many biologically active compounds. Additionally, it finds applications in material science for creating organic electronic materials and polymers.