3-Chloro-4-(piperidine-1-carbonyl)phenylboronic acid
98%
Reagent
Code: #163108
CAS Number
850589-50-3
blur_circular Chemical Specifications
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Molecular Information
Weight
267.5 g/mol
Formula
C₁₂H₁₅BClNO₃
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Registry Numbers
MDL Number
MFCD07363775
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Physical Properties
Melting Point
160-163 °C
Boiling Point
498.6 °C at 760 mmHg
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Storage & Handling
Storage
Room temperature, sealed, dry
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical development. Its boronic acid functionality enables formation of carbon-carbon bonds with aryl halides, making it valuable in constructing complex aromatic structures. Commonly applied in the preparation of protease inhibitors and kinase inhibitors due to the presence of both boronic acid and piperidine moieties, which enhance binding to enzyme active sites. Also utilized in medicinal chemistry for the development of boron-containing drugs with improved selectivity and metabolic stability.
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