(3-Chloro-5-fluoro-4-hydroxyphenyl)boronic acid
97%
Reagent
Code: #161925
CAS Number
1003298-72-3
blur_circular Chemical Specifications
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Molecular Information
Weight
190.36 g/mol
Formula
C₆H₅BClFO₃
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Registry Numbers
MDL Number
MFCD18447589
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Physical Properties
Boiling Point
335.5±52.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other biologically active compounds. Its structure allows for selective cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex aromatic systems. Commonly employed in Suzuki-Miyaura coupling reactions to form carbon-carbon bonds, enabling the creation of fluorinated and chlorinated biaryl motifs found in drug candidates. Also utilized in the preparation of protease inhibitors and anti-cancer agents due to its ability to enhance binding affinity and metabolic stability in target molecules.
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