(1-(tert-Butoxycarbonyl)-5-chloro-1H-indol-2-yl)boronic acid
98%
Reagent
Code: #154440
CAS Number
475102-12-6
blur_circular Chemical Specifications
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Molecular Information
Weight
295.53 g/mol
Formula
C₁₃H₁₅BClNO₄
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Registry Numbers
MDL Number
MFCD04039005
thermostat
Physical Properties
Boiling Point
471.4 °C at 760 mmHg
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Storage & Handling
Storage
-20°C, Sealed, Dry
description Product Description
Used as a key intermediate in the synthesis of indole-based pharmaceuticals, particularly in Suzuki-Miyaura cross-coupling reactions to construct biaryl frameworks. Its boronic acid group enables efficient carbon-carbon bond formation, making it valuable in drug discovery for developing bioactive molecules, including kinase inhibitors and serotonin receptor modulators. The Boc-protecting group ensures stability and selective reactivity during multi-step syntheses. Commonly applied in research settings for generating compound libraries in medicinal chemistry.
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