Used in Suzuki-Miyaura cross-coupling reactions to synthesize biaryl compounds, particularly in the development of pharmaceutical intermediates. The BOC-protected indole scaffold is valuable in medicinal chemistry for constructing nitrogen-containing heterocycles. Its boronic acid functionality allows for mild, selective coupling with aryl halides, making it useful in the synthesis of complex molecules for drug discovery, especially in the preparation of serotonin receptor modulators and other bioactive indole derivatives. The presence of the methyl group enhances electronic and steric properties, influencing coupling efficiency and selectivity.