1-Boc-3-methyl-1H-pyrazole-5-boronic Acid
≥95%
Reagent
Code: #148231
CAS Number
1217501-27-3
blur_circular Chemical Specifications
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Molecular Information
Weight
226.04 g/mol
Formula
C₉H₁₅BN₂O₄
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Registry Numbers
MDL Number
MFCD15143457
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Physical Properties
Boiling Point
394.5±52.0°C at 760 mmHg
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Storage & Handling
Storage
-20°C, stored in inert gas
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions to synthesize complex pyrazole derivatives, which are key scaffolds in pharmaceuticals and agrochemicals. The Boc-protected pyrazole ring provides stability and selectivity during coupling, while the boronic acid group enables efficient carbon-carbon bond formation. Commonly applied in drug discovery for building bioactive molecules, especially kinase inhibitors and anti-inflammatory agents. Its protected form allows for later deprotection and further functionalization in multi-step synthesis.
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