(5-Carbamoyl-2-fluorophenyl)boronic acid
98%
Reagent
Code: #132012
CAS Number
874289-39-1
blur_circular Chemical Specifications
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Molecular Information
Weight
182.95 g/mol
Formula
C₇H₇BFNO₃
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Registry Numbers
MDL Number
MFCD08436055
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Physical Properties
Melting Point
192-194 °C
Boiling Point
369.0±52.0 °C(Predicted)
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Storage & Handling
Density
1.41±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic acid functional group enables participation in Suzuki-Miyaura cross-coupling reactions, making it valuable in constructing biaryl frameworks found in bioactive molecules. Commonly employed in medicinal chemistry for lead optimization due to its ability to enhance binding affinity and metabolic stability. Also utilized in the preparation of fluorinated analogs to improve pharmacokinetic properties of drug candidates.
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