(4-(tert-Butylcarbamoyl)-3-fluorophenyl)boronic acid
98%
Reagent
Code: #132004
CAS Number
874289-18-6
blur_circular Chemical Specifications
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Molecular Information
Weight
239.05 g/mol
Formula
C₁₁H₁₅BFNO₃
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Registry Numbers
MDL Number
MFCD08689525
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Physical Properties
Melting Point
140-143 °C
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Storage & Handling
Density
1.20±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions for the synthesis of fluorinated biaryl compounds in pharmaceutical and agrochemical research. Its boronic acid group enables efficient carbon-carbon bond formation under mild conditions. The presence of a fluorine atom and a tert-butylcarbamoyl group enhances substrate selectivity and metabolic stability in drug development. Commonly employed in late-stage functionalization of complex molecules due to its compatibility with various functional groups. Also applied in the preparation of kinase inhibitors and other bioactive molecules where fluorinated aromatic scaffolds are required.
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