(2-Fluoro-5-(pyrrolidine-1-carbonyl)phenyl)boronic acid
98%
Reagent
Code: #131071
CAS Number
874289-42-6
blur_circular Chemical Specifications
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Molecular Information
Weight
237.04 g/mol
Formula
C₁₁H₁₃BFNO₃
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Registry Numbers
MDL Number
MFCD08436030
thermostat
Physical Properties
Melting Point
146-148 °C
Boiling Point
471.4±55.0 °C(Predicted)
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Storage & Handling
Density
1.32 g/cm3
Storage
Room temperature, seal, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its boronic acid functionality enables Suzuki-Miyaura cross-coupling reactions, allowing efficient construction of biaryl structures in drug molecules. Commonly employed in medicinal chemistry for optimizing lead compounds due to its ability to enhance binding affinity and metabolic stability. Also utilized in the preparation of protease inhibitors and targeted therapies where fluorinated aromatic systems improve pharmacokinetic properties.
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