3,3-Difluoro-2,2-dimethyl-1-indanone
95%
Reagent
Code: #172499
CAS Number
1034921-55-5
blur_circular Chemical Specifications
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Molecular Information
Weight
196.19 g/mol
Formula
C₁₁H₁₀F₂O
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Registry Numbers
MDL Number
MFCD20482497
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its rigid indanone scaffold with fluorinated substituents enhances metabolic stability and binding affinity in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate lipophilicity and electronic properties. Also utilized in the preparation of fluorinated analogs to improve pharmacokinetic profiles in CNS-targeted therapeutics.
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