1-(2-Bromophenyl)-2,2,2-trifluoroethanone
95%
Reagent
Code: #152445
CAS Number
244229-34-3
blur_circular Chemical Specifications
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Molecular Information
Weight
253.02 g/mol
Formula
C₈H₄BrF₃O
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Registry Numbers
MDL Number
MFCD07380806
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Physical Properties
Boiling Point
230.0±40.0 °C(Predicted)
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Storage & Handling
Density
1.645 g/cm3 at 25 °C
Storage
Room temperature, seal, dry
description Product Description
Used primarily as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its structure allows for selective functionalization in heterocyclic compound formation, particularly in the development of fluorinated bioactive molecules. The presence of both bromine and trifluoromethyl groups enables cross-coupling reactions and nucleophilic substitutions, making it valuable in medicinal chemistry for building complex molecules with enhanced metabolic stability and binding affinity. It is also employed in the preparation of fluorinated analogs of natural products for structure-activity relationship studies.
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