1-(4-Aminophenyl)-2,2,2-trifluoro-1-ethanone
95%
Reagent
Code: #137233
CAS Number
23516-79-2
blur_circular Chemical Specifications
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Molecular Information
Weight
189.13 g/mol
Formula
C₈H₆F₃NO
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Registry Numbers
MDL Number
MFCD05663790
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Physical Properties
Melting Point
92-94°C
Boiling Point
269.1°C at 760 mmHg
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Storage & Handling
Storage
Protect from light, 2-8℃
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of selective kinase inhibitors and anti-inflammatory agents. Its trifluoromethyl ketone group enables strong hydrogen bonding and metabolic stability, making it valuable in medicinal chemistry for enhancing drug potency and bioavailability. Also employed in the preparation of fluorescent probes and dyes due to its electron-withdrawing properties and aromatic amine functionality, which can be further modified for specific sensing applications.
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