(E)-1-phenylbut-2-en-1-one finds application in the fragrance and flavor industry, where it is utilized for its sweet, balsamic, and slightly floral aroma. It is often incorporated into perfumes, cosmetics, and personal care products to enhance scent profiles. Additionally, it serves as a key intermediate in organic synthesis, particularly in the production of pharmaceuticals and fine chemicals. Its conjugated enone structure makes it a valuable building block in various chemical reactions, including Michael additions and cyclization processes. In research, it is also used as a model compound to study reaction mechanisms and develop new synthetic methodologies.