2-Fluorophenethyl isocyanate
98%
Reagent
Code: #188402
CAS Number
480439-39-2
blur_circular Chemical Specifications
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Molecular Information
Weight
165.16 g/mol
Formula
C₉H₈FNO
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Registry Numbers
MDL Number
MFCD04039911
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Physical Properties
Melting Point
212-213°C
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Storage & Handling
Density
1.152g/ml
Storage
Room temperature, stored in inert gas
description Product Description
Used primarily as a specialty reagent in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its isocyanate group readily reacts with amines and alcohols, making it valuable for constructing urea and urethane derivatives. The fluorine substituent influences reactivity and binding properties, which is advantageous in medicinal chemistry for modifying bioavailability and metabolic stability of drug candidates. It also serves as an intermediate in the preparation of fluorinated analogs of biologically active molecules, where the fluorine atom can enhance target selectivity or improve pharmacokinetic profiles. Due to its lachrymatory and reactive nature, handling requires strict safety controls, limiting its use to controlled laboratory and industrial research settings.
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