1-Bromo-4-(difluoromethoxy)benzene
97%
Reagent
Code: #143435
CAS Number
5905-69-1
blur_circular Chemical Specifications
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Molecular Information
Weight
223.01 g/mol
Formula
C₆H₄BrOCHF₂
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Registry Numbers
MDL Number
MFCD00221465
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Physical Properties
Boiling Point
96 °C
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Storage & Handling
Density
1.631 g/mL at 25 °C(lit.)
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated organic compounds. Its difluoromethoxy group enhances metabolic stability and lipophilicity, making it valuable in medicinal chemistry for optimizing drug candidates. Commonly employed in cross-coupling reactions, such as Suzuki or Ullmann reactions, to introduce the difluoromethoxyphenyl moiety into larger molecules. Also utilized in the preparation of liquid crystals and functional materials where electronic and steric properties are critical.
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