1-Fluoro-4-(trifluoromethoxy)benzene
99%
Reagent
Code: #187199
Alias
4-(trifluoromethoxy)fluorobenzene
CAS Number
352-67-0
blur_circular Chemical Specifications
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Molecular Information
Weight
180.1 g/mol
Formula
C₇H₄F₄O
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Registry Numbers
EC Number
206-523-2
MDL Number
MFCD00040835
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Physical Properties
Boiling Point
104-105 °C(lit.)
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Storage & Handling
Density
1.323 g/mL at 25 °C(lit.)
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of fluorinated compounds with enhanced metabolic stability and bioavailability. Its fluorinated aromatic structure makes it valuable in medicinal chemistry for modifying drug candidates to improve their lipophilicity and resistance to oxidative degradation. Commonly employed in the preparation of selective serotonin reuptake inhibitors (SSRIs) and other bioactive molecules where fluorine substitution plays a critical role in activity. Also utilized in the creation of specialty materials and liquid crystals due to its unique electronic and steric properties.
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