1-(tert-Butoxy)-4-(trifluoromethyl)benzene
95%
Reagent
Code: #151806
CAS Number
16222-44-9
blur_circular Chemical Specifications
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Molecular Information
Weight
218.22 g/mol
Formula
C₁₁H₁₃F₃O
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Registry Numbers
MDL Number
MFCD09763645
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Physical Properties
Boiling Point
218 ℃
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Storage & Handling
Density
1.110 g/cm3
Storage
Room temperature, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions where the trifluoromethyl group enhances metabolic stability and lipophilicity. Its tert-butoxy functionality serves as a protecting group or directing moiety in organic transformations. Commonly employed in the development of fluorinated compounds for medicinal chemistry due to the favorable electronic and steric properties imparted by the CF3 group. Also utilized in the preparation of liquid crystals and functional materials where fluorinated aromatics improve thermal and oxidative stability.
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