Tetrafluorophthalic acid is primarily used in the synthesis of advanced polymers and resins. Its incorporation into polymer chains enhances thermal stability and chemical resistance, making it valuable in high-performance coatings and adhesives. The compound is also utilized in the production of specialty plastics that require durability under harsh conditions. Additionally, it serves as a key intermediate in the development of liquid crystal polymers, which are essential for electronic displays and optical devices. Its unique fluorinated structure contributes to low surface energy properties, making it suitable for applications in water-repellent and anti-fouling materials.