3,3'-Bis(trifluoromethyl)benzidine is primarily used as a diamine monomer in the synthesis of high-performance polyimides and as a curing agent for epoxy resins. Its fluorinated structure enhances the thermal stability, chemical resistance, and mechanical properties of the resulting polymers, making them suitable for demanding applications in aerospace, electronics, and industrial coatings. It is also employed in specialty polymer synthesis requiring resistance to harsh environments. Due to its structural similarity to benzidine, a known carcinogen, handling is strictly controlled, and it is not used in consumer-facing products.