Divinylbenzene is widely used as a cross-linking agent in the production of polymers and resins. It enhances the mechanical strength, thermal stability, and chemical resistance of materials, making it essential in manufacturing ion-exchange resins, which are crucial for water purification and chemical separation processes.

In the plastics industry, it is utilized to create durable and heat-resistant products, such as coatings, adhesives, and composite materials. Additionally, it serves as a key component in the synthesis of specialty polymers, including those used in chromatography and solid-phase peptide synthesis.

Its ability to form highly cross-linked networks also makes it valuable in the production of microspheres and beads for applications in drug delivery, diagnostics, and catalysis. Divinylbenzene's versatility and robust properties contribute significantly to advancements in materials science and industrial chemistry.