4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic acid
97%
Reagent
Code: #240766
CAS Number
199528-28-4
blur_circular Chemical Specifications
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Molecular Information
Weight
266.22 g/mol
Formula
C₁₄H₉F₃O₂
thermostat
Physical Properties
Boiling Point
377.5°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules. Its structure allows for enhanced metabolic stability and binding affinity due to the electron-withdrawing trifluoromethyl group. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies. Also utilized in the preparation of liquid crystal materials and organic semiconductors owing to its rigid biphenyl framework and polarity.
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