Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules targeting central nervous system disorders. Its structural features, including the difluorocyclobutane ring and halogenated aromatic group, enhance metabolic stability and binding selectivity in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its rigid framework and ability to influence pharmacokinetic properties. Also utilized in the preparation of receptor modulators and enzyme inhibitors, where the amine functionality allows for further derivatization into amides, sulfonamides, or ureas.