tert-Butyl2-bromo-3-fluorobenzylcarbamate
98%
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description Product Description
Used as a protected intermediate in the synthesis of pharmaceutical compounds, where the tert-butyl carbamate (Boc) group safeguards the amino functionality during multi-step reactions, enhancing reaction selectivity and minimizing byproducts. The Boc group can be readily removed under acidic conditions to reveal the free amine for subsequent transformations. Particularly valuable in the development of bioactive molecules targeting central nervous system disorders, antimicrobials, antivirals, and analgesics. The bromine and fluorine substituents on the benzene ring enable further derivatization, such as nucleophilic substitutions or cross-coupling reactions (e.g., copper-catalyzed couplings), to introduce fluorinated benzyl groups that improve metabolic stability, binding affinity, and environmental profiles in drug and agrochemical candidates.
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