2-Bromo-1-ethynyl-4-fluorobenzene
98%
Reagent
Code: #155659
CAS Number
1057670-01-5
blur_circular Chemical Specifications
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Molecular Information
Weight
199.02 g/mol
Formula
C₈H₄BrF
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Registry Numbers
MDL Number
MFCD08703532
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in cross-coupling reactions such as Sonogashira coupling to form conjugated aryl alkynes. Its bromo and ethynyl functional groups allow for sequential functionalization, making it valuable in building complex organic molecules. Commonly employed in the development of fluorinated bioactive compounds where the fluorine atom enhances metabolic stability and binding affinity. Also applied in materials science for constructing π-conjugated systems used in organic electronics.
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