4-Bromo-1-ethynyl-2-fluorobenzene
97%
Reagent
Code: #155591
CAS Number
302912-33-0
blur_circular Chemical Specifications
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Molecular Information
Weight
199.03 g/mol
Formula
C₈H₄BrF
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Registry Numbers
MDL Number
MFCD02683523
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in cross-coupling reactions such as Sonogashira coupling to form complex aromatic systems. Its ethynyl and bromo functional groups allow for sequential derivatization, making it valuable in the development of bioactive molecules and functional materials. Commonly employed in the preparation of fluorinated analogs in medicinal chemistry, where the fluorine atom enhances metabolic stability and binding affinity. Also applied in the construction of conjugated organic compounds for use in materials science, including semiconductors and liquid crystals.
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