3-(4-Bromo-3-fluorophenyl)propiolicacid
95%
Reagent
Code: #155241
CAS Number
1339425-98-7
blur_circular Chemical Specifications
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Molecular Information
Weight
243.03 g/mol
Formula
C₉H₄BrFO₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used in organic synthesis as an intermediate for pharmaceuticals and agrochemicals, particularly in the preparation of fluorinated and brominated aromatic compounds. The bromine substituent enables Pd-catalyzed cross-coupling reactions, such as Suzuki-Miyaura coupling, to introduce diverse aryl or heteroaryl groups. The conjugated alkyne and carboxylic acid functional groups facilitate further derivatizations, including amidation, esterification, or alkyne-specific transformations like hydration or Diels-Alder cycloadditions, enabling the construction of complex molecules. Commonly employed in medicinal chemistry for developing bioactive compounds due to the enhanced metabolic stability and binding affinity provided by the fluorine and bromine substituents. Also utilized in materials science for synthesizing conjugated systems in organic electronics.
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