3-[(tert-Butyldimethylsilyl)oxy]-4-methoxybenzaldehyde
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Used primarily as an intermediate in organic synthesis, especially in the pharmaceutical and fine chemical industries. It serves as a protected form of a catechol-type phenol, where the silyl ether group provides stability during multi-step reactions. Commonly employed in the synthesis of natural products and bioactive molecules, particularly alkaloids and flavonoids, due to its ability to selectively protect hydroxyl groups while allowing further functionalization at the aldehyde moiety. Its methoxy and aldehyde groups enable condensation and coupling reactions, making it valuable in constructing complex aromatic frameworks. The tert-butyldimethylsilyl (TBS) group can be removed under mild conditions, allowing for controlled deprotection in sensitive synthetic pathways.
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