Used primarily as a reagent in organic synthesis, particularly in the preparation of fluorinated aromatic compounds. It serves as a building block in pharmaceutical development, where the difluorophenyl moiety is present in bioactive molecules. Its reactivity as an electrophile allows for the formation of ketones and heterocycles through condensation and cyclization reactions. Commonly employed in the synthesis of drug intermediates targeting central nervous system disorders and inflammatory conditions. Also utilized in the modification of peptides and proteins due to its ability to react selectively with arginine residues, enabling biochemical probing and labeling applications.