3'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbaldehyde
96%
Reagent
Code: #129229
CAS Number
223575-93-7
blur_circular Chemical Specifications
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Molecular Information
Weight
250.22 g/mol
Formula
C₁₄H₉F₃O
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Registry Numbers
MDL Number
MFCD03424643
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Physical Properties
Boiling Point
339.0±42.0 °C(Predicted)
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Storage & Handling
Density
1.281 g/cm3 at 25 °C
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of angiotensin II receptor antagonists for treating hypertension. Its structure allows for the introduction of trifluoromethyl groups, which can enhance metabolic stability and binding affinity in drug molecules. Also employed in the preparation of liquid crystal compounds for display technologies due to its rigid biphenyl framework and electronic properties. Commonly utilized in Suzuki and other cross-coupling reactions to build complex aromatic systems in medicinal chemistry research.
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