CD437 is primarily investigated for its potential applications in cancer research and dermatology due to its ability to induce apoptosis in various cancer cell lines. It has shown promise in targeting melanoma cells by promoting cell death and inhibiting tumor growth. Additionally, CD437 is studied for its role in skin health, particularly in the regulation of keratinocyte differentiation and its potential use in treating skin disorders such as psoriasis. Its retinoid-like properties make it a candidate for developing novel therapeutic agents in both oncology and dermatology. Research continues to explore its mechanisms and efficacy in these areas.