Used in biochemical research as a nucleotide analog, particularly in studies involving viral replication inhibition and enzyme activity related to antiviral mechanisms. It serves as a key intermediate in the synthesis of modified nucleotides that mimic natural substrates, enabling investigation of viral polymerases and nucleoside kinases. Its structure allows incorporation into viral DNA/RNA synthesis pathways, making it valuable in drug development for antiviral therapies against HIV and HBV. Also employed in the design of prodrugs due to its esterified form, enhancing cell membrane permeability.