(E)-4-(Ethoxycarbonyl)-4-amino-2-methylbut-2-enylphosphonicacid;(R,E)-(4-amino-5-ethoxy-2-methyl-5-oxopent-2-en-1-yl)phosphonic acid

≥99%

Reagent Code: #186319
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CAS Number 127910-32-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 237.19 g/mol
Formula C₈H₁₆NO₅P
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

Used as a key intermediate in the synthesis of antiviral and antiretroviral drugs, particularly in the development of nucleotide analogs that inhibit viral polymerase enzymes. Its phosphonate group mimics phosphate groups in nucleotides, allowing it to integrate into viral DNA or RNA chains and terminate chain elongation. This compound is especially valuable in prodrug formulations designed to enhance cellular uptake and bioavailability. It also serves in medicinal chemistry research for designing enzyme inhibitors targeting herpesviruses, hepatitis B, and HIV. Additionally, its structural features make it useful in studying structure-activity relationships in phosphorylated metabolites.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿25,490.00
inventory 10mg
10-20 days ฿35,680.00

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