Doravirine is used in the treatment of human immunodeficiency virus type 1 (HIV-1) infection. It is part of antiretroviral therapy and works by inhibiting the reverse transcriptase enzyme, which is essential for viral replication. This helps reduce the amount of virus in the body, allowing the immune system to recover and function more effectively. Doravirine is often combined with other antiretroviral agents to improve treatment efficacy and reduce the risk of drug resistance. It is suitable for use in treatment-naïve adults and may be preferred in certain patients due to its favorable side effect profile and low impact on lipid levels.