Cabotegravir (GSK744, GSK1265744)
10mM in DMSO
Reagent
Code: #158030
CAS Number
1051375-10-0
blur_circular Chemical Specifications
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Molecular Information
Weight
405.35 g/mol
Formula
C₁₉H₁₇F₂N₃O₅
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Registry Numbers
MDL Number
MFCD25976748
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Storage & Handling
Storage
-20°C
description Product Description
Used in the prevention and treatment of HIV-1 infection. Acts as an integrase strand transfer inhibitor, blocking the viral integrase enzyme to prevent HIV from replicating in human cells. Administered as a long-acting injectable formulation, it provides sustained drug levels, allowing for monthly or less frequent dosing. This makes it suitable for pre-exposure prophylaxis (PrEP) in high-risk individuals and as part of antiretroviral therapy (ART) in diagnosed patients, improving adherence compared to daily oral regimens.
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