1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine
95%
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This imidazoquinoline derivative serves as a potent immune response modifier in pharmaceutical research, activating the innate immune system via Toll-like receptors 7 and 8 (TLR7/8). It is investigated as a synthetic intermediate and active analog for developing topical and systemic therapies against viral infections (e.g., HPV-related warts), skin conditions like actinic keratosis, and certain cancers including basal cell carcinoma. The compound promotes local cytokine production, such as interferon-alpha and pro-inflammatory mediators, aiding in immune-mediated clearance of lesions. Additionally, it holds potential as an adjuvant in vaccine development for enhancing immune responses against infectious diseases like hepatitis or HIV. Its targeted activation profile supports low systemic absorption in topical applications, contributing to a favorable research safety profile.
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