GS-7340, also known as Tenofovir Alafenamide, is primarily used in the treatment of HIV infections. It functions as a prodrug of tenofovir, which means it is converted into its active form within the body to exert its antiviral effects. This compound is particularly effective in inhibiting the reverse transcriptase enzyme, a crucial component in the replication of the HIV virus. By blocking this enzyme, GS-7340 helps to reduce the viral load in patients, thereby slowing the progression of the disease. It is often included in combination therapies to enhance its efficacy and to minimize the risk of developing drug resistance. Due to its improved pharmacokinetic properties, GS-7340 allows for lower doses compared to its predecessor, tenofovir disoproxil fumarate, reducing the potential for side effects while maintaining therapeutic effectiveness. This makes it a valuable component in the management of HIV, contributing to better patient outcomes and improved quality of life.