Podophyllin is primarily used in the medical field for its topical application in treating certain skin conditions. It is commonly applied to remove genital warts caused by the human papillomavirus (HPV). The chemical works by inhibiting cell division, leading to the destruction of the wart tissue. It is applied directly to the affected area by a healthcare professional to avoid damage to surrounding healthy skin. Additionally, podophyllin has been explored for its potential in treating other skin growths and conditions, though its use is strictly controlled due to its potent and potentially toxic nature. Proper application and adherence to medical guidelines are essential to ensure safety and effectiveness.