Phosphonic acid,P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-,hydrate (1:2)
>99%
Reagent
Code: #76881
CAS Number
149394-66-1
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
279.18 g/mol
Formula
C₈H₁₄N₃O₆P
thermostat
Physical Properties
Melting Point
260ºC
Boiling Point
609.5ºC
inventory_2
Storage & Handling
Density
1.76g/cm3
Storage
room temperature, dry
description Product Description
This compound, known as Cidofovir hydrate, is an antiviral medication primarily used in the treatment of cytomegalovirus (CMV) retinitis and other infections caused by herpesviruses in immunocompromised patients, such as those with AIDS. As an acyclic nucleoside phosphonate analog, it mimics natural nucleotides and is incorporated into viral DNA, where it inhibits viral DNA polymerase and causes chain termination, thereby preventing viral replication. Its role is crucial in managing opportunistic viral infections and has been studied for broader applications against DNA viruses.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | white solid |
| Purity | 98.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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