(2R,5S)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
≥95%
Reagent
Code: #113164
CAS Number
764659-72-5
blur_circular Chemical Specifications
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Molecular Information
Weight
399.48 g/mol
Formula
C₁₈H₂₆FN₃O₄S
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Registry Numbers
MDL Number
MFCD09753268
thermostat
Physical Properties
Boiling Point
508.5±60.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, stored in an inert gas
description Product Description
This compound serves as a crucial synthetic intermediate in the production of antiviral nucleoside analogs, notably Emtricitabine, which is employed in treating retroviral infections like HIV and hepatitis B virus (HBV). The ester group facilitates stereochemical resolution and protection during synthesis, enabling the creation of the active pharmaceutical ingredient that inhibits reverse transcriptase, thereby blocking viral replication, reducing viral load, and managing disease progression. Ongoing research explores its role in developing improved antiviral therapies with enhanced efficacy and reduced side effects.
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